产品货号:
Z37019
中文名称:
PCBP2抗体
英文名称:
Anti-PCBP2 Antibody (Clone#4B9C7)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PCBP2 Antibody (Clone#4B9C7) |
指标别名 | Alpha CP2;hnRNP E2;HNRPE2;PCBP2;poly(rC) binding protein 2 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF,FCM |
基因名称 | PCBP2 |
克隆号 | 4B9C7 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | E.coli-derived human PCBP2/hnRNP E2 recombinant protein (Position:Q197-K276). |
实际分子量 | 39KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Poly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene.The protein encoded by this gene appears to be multifunctional.Along with PCBP-1 and hnRNPK,it is one of the major cellular poly(rC)-binding proteins.The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding.Together with PCBP-1,this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES,promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.It has also been implicated in translational control of the 15-lipoxygenase mRNA,human papillomavirus type 16L2 mRNA,and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1,an intronless gene with functions similar to that of PCBP2.This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes.This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2).Multiple transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | Q15366 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for ICC. |
基因名全称 | poly(rC) binding protein 2 |
蛋白名全称 | Poly(rC)-binding protein 2 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells |
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